The working group is made up of neurologists, clinical and experimental neuroscientists, engineers, physicists, lab technitians, vets, nurses and others, who have obtained their specialty in national centres and carried out post-doctoral training in internationally renowned centres. The essence of the activity of HM CINAC lies in interaction and transversal collaboration, with the common objective of impacting on neurodegenerative diseases. In this way, the main axis of HM CINAC is provided by the patients themselves, whose clinical manifestations and problems guide our main research topics.


About us


The activity of HM CINAC in the clinical care, research and experimental clinical aspects is integrated into a homogeneous and transversal set.

The HIFU allows the Treatment of Essential Tremor and Parkinson's disease without Surgery.

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The activities of HM CINAC Madrid have the following objectives:


Research in Clinical Neuroscience

Focused on neurodegenerative diseases such as Parkinson's disease, cognitive decline, and behavioral disorders with a comprehensive approach.

We apply advanced methods of neuroimaging (integrated fMRI-PET), neurophysiology (non-invasive neurostimulation, movement studies, and recording of oscillatory activity), neurocognitive stimulation (behavioral laboratory), and neurosurgical stimulation (deep brain stimulation, focal ultrasound therapy) to advance and develop new therapeutic options for Parkinson's disease and other neurodegenerative diseases, as well as movement and behavioral disorders (dystonia, myoclonus, pathological impulsivity, Gilles de la Tourette syndrome, etc.).


Development of fundamental knowledge through Experimental Neuroscience

For which HM CINAC has a preclinical research center that works on the neurobiological mechanisms of neurological diseases. This approach is based on neuroimaging methods (PET and fMRI), neurophysiological techniques that allow comprehensive studies of unit, multiple, and field potential neuronal activity, behavioral laboratories, and histopathological techniques.


Series of national and international collaborations

They create a joint leadership and network with the common goal of advancing in the fight against neurodegenerative diseases and neurofunctional disorders.

HM Cinac's effort is unique and directly aimed at developing pathophysiological concepts that achieve therapeutic advances to help the quality of life of patients. In this initial period, HM CINAC's specific interest is focused on stopping the progression of Parkinson's disease from studies in functional neuroscience and PET, focal ultrasound, genetics, magnetic stimulation, cognitive impairment and experimental neurology.

During the last years we cooperate, in terms of training and medical assistance with different universities abroud. HM CINAC ( Comprehensive Neuroscience Centre) in terms of Parkinson and neurological movement disorder's diseases signed an agreement with Aarhus University Hospital, patients coming from Denmark have been assisted during the last 3 years in HM CINAC, Aarhus University Hospital is the largest single hospital in Denmark and one of the largest in Europe. 


Neuroscience Center Madrid

Clinical Services Neuroscience Center

The Clinical Neurosciences section offers the study and treatment of neurodegenerative diseases in outpatient, day hospital and hospitalization.

At HM CINAC we carry out the study and treatment of neurodegenerative diseases through an ambulatory, day hospital and general hospital. There are specialized programs in:

a) Study and treatment of Parkinson's disease and movement disorders;

b) Cognitive impairment (in collaboration with the Psychiatry service);

c) Conduct Disorders (in collaboration with the Psychiatry service);

d) Advanced neurophysiological studies of motor control, cognition and behavior;

e) Functional Neurosurgery: Deep Brain Stimulation, Focal Ultrasound and classic ablative surgery.

f) Psychiatry and Clinical Psychology

g) HIFU treatments for essential tremor and Parkinson's disease:  SEE THIS VIDEO click here

Main Work Areas HM CINAC

• Selective vulnerability of dopaminergic cells in the ventro-lateral pars compact substantia nigra: anatomo-physiological factors and mechanisms

• Anatomo-functional basis of automatic movements: Neurosciences of habitual or routine activity.

• Compensatory Mechanisms, Inflammation and progression of Parkinson's disease

• Initiation and progression of Parkinson's disease: motor-cognitive pattern and structural and functional correlate

• Bases of pathological impulsivity and Parkinson's disease: Mechanisms and treatments

• New therapeutic perspectives in Parkinson's disease:


    a) Impact of early functional recovery using ultrasound

    b) Value of Magnetoceutical in the treatment of Parkinson's disease


• Impact of preferential and multi-disciplinary care on Parkinson's disease: Comparison of early-onset vs late-onset patients.





Treating Parkinson's disease and Essential Tremor with HIFU High Intensity Focal Ultrasound

Essential tremor and Parkinson's disease are very common neurological ailments that can condition great disability and dependency in patients who suffer from them.


The HIFU allows the Treatment of Essential Tremor and Parkinson's disease without Surgery.


What is HIFU?

It is the first system in Spain intended for the treatment of neurofunctional disorders. Using an ultrasound technique and magnetic resonance imaging - only compatible with a 3T MRI, also available at HM CINAC.

This process consists in applying to a target of a few millimeters, an ultrasound treatment that it generates localized hyperthermia and finally, ablation of the target zone. With this acquisition, HM CINAC becomes one of the few European centers where this treatment can be performed. In fact, Spain is the second country in Europe, along with Switzerland, which has the HIFU.


The main advantage of HIFU is that there is no need to perform an intracranial approach. During treatment, it is possible to see if the target and the effect are adequate, at the same time that corrections can be made to improve effectiveness and reduce adverse effects before producing focal tissue ablation.




Are you a good candidate for HIFU?

Neurological Consultation

1. Neurology Consultation. In this, a complete neurological evaluation will be carried out and the neurologist will decide if you are a potential candidate, for which, a series of tests must be carried out in order to assess that you are suitable and to rule out possible causes that contraindicate the procedure.

Neuropsychological Assessment

2. The next thing is to carry out a neuropsychological assessment by the Neuropsychologist of the team with the intention of verifying that their memory and other cognitive functions are preserved, which is important to guarantee the success of the treatment.

Magnetic Resonance and Tomography

3. Two imaging tests will be carried out: Magnetic Resonance and Skull CT, which have to meet specific parameters for performing the HIFU.


Multidisciplinary meeting

4. Finally, after all these tests, it will be assessed and decided, in a multidisciplinary meeting of the entire team, if you are suitable for treatment.


HIFU is indicated for patients affected by essential tremor and other tremors that can be treated with thalamic surgery, although its main application in the near future will be in Parkinson's disease and possibly in brain tumors, chronic pain, trigeminal neuralgia, some neuropsychiatric disorders, etc.


Phases Treatment Essential Tremor and Parkinson's disease with HIFU

The procedure has a total duration of 3-4 hours:

• In the first, the target or location chosen on which the ultrasound beams will act will be made by taking images.

• In the second, the treatment as such, ultrasound beams (called sonication) will be launched at the target point.


The ultrasounds will increase the temperature of the brain tissue in a progressive and controlled manner, until the injury is performed and the treatment is terminated, and a continuous evaluation of the patient will be carried out to verify its efficacy.


HIFU multidisciplinary team

The HIFU technique is carried out by a multidisciplinary team consisting of:

- Dr. Raúl Martínez - Neurologist

- Dra. Marta del Álamo - Neurosurgeon

- Dr. Ignacio Obeso - Neuropsychologist

As well as image engineers and technicians and nursing personnel.


This entire team is led by Dr. José A. Obeso Director of HM CINAC.

HM CINAC Móstoles-Madrid

Avenida Carlos V, 70 - 28938, Móstoles


How to get to HM CINAC

By private vehicle:

+ Extremadura A-5 motorway

+ M-50

+ M-50 Road from Villaviciosa de Odón-Fuenlabrada


By public transport:

+ Madrid-Móstoles bus lines: 521-522-523

+ Intercity bus lines:

   498 (Móstoles-Arroyomolinos-La Moraleja de Enmedio-Fuenlabrada)

    499 (Móstoles-Arroyomolinos)

    519 (Móstoles-Villaviciosa de Odón)

    520 (Alcorcón-Móstoles)

+ Móstoles interurban lines: 1 and 4

+ Metro Sur: Line 12, nearby stops: Manuela Malasaña / Pradillo Station


Request appointment / information HIFU treatment

For more information:

HM Cinac Revista 12P OK_EN.pdf


Neurosciences HM CINAC Barcelona

 Medical team

> Neurology

Dra. Beatriz Chavarría Cano

Dra. Marisol López Rodríguez


> Neurosurgery

Dr. Gerardo Conesa Bertrán

Column Unit

Dr. Francesco Caiazzo


> Neurophysiology

Dra. Estela Lladó Carbó

Dr. Mauricio David Díaz Sardi

Dr. Salvador de la Torre Orozco

Dra. Marta Cecília Flores

Dra. Alba León Jorba

Dr. Joé Antonio Reyes Pinto



> Interventional Neuroradiology

Dra. Teresa Solà

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